The Relationship Between the Mechanisms of Action and Safety Profiles of Intrathecal Morphine and Ziconotide: A Review of the Literature

Objective To better characterize safety profiles associated with the intrathecal (IT) administration of morphine and ziconotide and discuss how they relate to mechanisms of action. Methods Published data were evaluated to identify potential relationships between safety profiles of IT morphine and IT ziconotide and their mechanisms of action. Results Potentially severe and clinically relevant adverse…

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A Painful Homecoming for Soldiers

Nearly half of all soldiers returning from Afghanistan and Iraq have chronic pain. This is in contrast to the civilian rate of about 26%.  The prevalence of chronic pain in returning soldiers and veterans is unprecedented and probably related to the types of injuries and improved survival rates from successful medical interventions in the field. …

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Lessons Learned From Abington Memorial Hospital’s New Institutional Methadone Policy

Maria C. Foy, PharmD, remembers the patient who first piqued her research interest in methadone policy—a pregnant, recovering heroine addict on methadone therapy who presented to Abington Memorial Hospital in Abington, Pa. “The incident made us aware that there was a real lack of understanding and knowledge on the use of methadone and the differences…

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Guest Post: Barby Ingle on Chronic Pain and Opioids

By Barby Ingle, President Power of Pain Foundation Imagine going from living an active life, where dance was a central part of your life, to living in pain that limits your every move. It happened to me. As head of Washington State University’s cheer and dance programs, physical fitness was a central and wonderful part…

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Fixing the Chronic Pain Care Catch-22

Healthcare providers in the U.S. are poorly prepared to manage chronic pain, according to the National Institutes for Health. No argument here. Time Magazine’s Alexandra Sifferlin does an excellent job covering the January NIH report on this deepening crisis. But she ignores a crucial factor: how to pay for the interdisciplinary care that the NIH…

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A Chorus of Change

The movie “Cake” starring Jennifer Aniston will be released Jan. 23rd. I will definitely be in the audience when it opens, and I urge everyone else to see it. Aniston stars as Claire, a woman who suffers from chronic pain. She becomes obsessed with the suicide death of one of the members of her support…

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